контрактне виробництво
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виробництво торгова марка
METHYLURACIL
Release form
Rectal suppositories
For children
Contraindicated for children under 14 years of age
For pregnant women
Contraindicated
For nursing mothers
Contraindicated
For drivers
Contraindicated
Storage temperature
until 15 °C
INSTRUCTION
storage
active substance: methyluracil; 1 suppository contains 0.5 g of methyluracil; excipient: solid fat.
Medicinal form
Rectal suppositories. The main physicochemical properties: suppositories are white or white with a yellowish or cream tint.
Pharmacotherapeutic group
Non-steroidal anabolic agents Code ATX A14B.
Pharmacological properties
Pharmacodynamics. The drug has an anabolic and anti-catabolic effect. Accelerates regeneration, wound healing, stimulates cellular and humoral links of immunity, has an anti-inflammatory effect. A characteristic specific property of the drug is its stimulating effect on erythro- and, especially, leukopoiesis. Pharmacokinetics. When a suppository is inserted into the rectum, the drug is well and almost completely absorbed through the mucosa and is detected in the blood after 20–30 minutes. The maximum concentration in the blood is reached after 1–2 hours. It is excreted from the body mainly by the kidneys in the form of metabolites and conjugates and partly with feces in an unchanged form.
Indication
Inflammatory-ulcerative diseases of the lower parts of the large intestine: erosive-ulcerative colitis, proctosigmoiditis, anal fissures.
Contraindication
Hypersensitivity to methyluracil or other components of the drug. The drug is contraindicated in acute and chronic (usually myeloid) forms of leukemia, lymphogranulomatosis, malignant bone marrow diseases.
Interaction with other medicinal products and other forms of interaction
Methyluracil enhances the effect of strophanthin, increases the effectiveness of antibiotics and sulfonamide drugs.
Features of use
Methyluracil should be prescribed for mild forms of leukopenia. In the case of a disease of medium severity, the drug should be taken only after restoration of blood cell regeneration disorders. Methyluracil should not be prescribed for severe forms of damage to hematopoiesis. Use during pregnancy or breastfeeding. The drug is not used during pregnancy or breastfeeding. The ability to influence the speed of reaction when driving vehicles or other mechanisms. Until the patient's individual reaction to the drug is clarified, one should refrain from driving a motor vehicle or working with other mechanisms, given that during treatment with methyluracil such adverse reactions from the nervous system as dizziness are possible.
Methods of application
Release the suppository from the contour packaging and enter rectally. Adults and children over 14 years old: 1 suppository 1-4 times a day. The course of treatment is from 7 days to 4 months, depending on the nature of the disease. Children. The drug should not be used for the treatment of children under 14 years of age.
Overdose
Not observed.
Side effects
From the side of the central nervous system: headache, dizziness. From the side of the skin and subcutaneous tissue: allergic reactions, including hyperemia, itching, skin rashes, urticaria. Changes in the injection site: when a suppository is inserted into the rectum, a short-term burning, itching is sometimes felt.
Expiration date
2 years.
Storage conditions
In the original package at a temperature not higher than 15 ºС. Keep out of the reach of children.
Packaging
5 suppositories in a strip. 2 strips in a cardboard pack.
Leave category
Without a prescription.
Producer
Monfarm PJSC.
Address
Ukraine, 19161, Cherkasy region, Uman district, village Avramivka, str. Zavodska, 8.